DNA Fragmentation Testing
DNA fragmentation assay is the most important sperm function test.
DNA fragmentation assay is the most important sperm function test. The method detects the presence of DNA fragments using the most advanced SCD method. It evaluates the integrity of the DNA molecule, whereby high levels may be associated with:
- Age (> 40)
- Unhealthy lifestyle (smoking, alcohol, etc.)
- Increased oxidative stress
The test is recommended to couples with:
- Low pregnancy success rates
- Poor embryo quality
- Suspended embryo development
- Recurrent miscarriages
High rates of congenital abnormalities in offspring.
DNA fragmentation may also possibly exist in cases when the remaining sperm parameters are within normal levels. Special lab semen treatment techniques are recommended in samples with high fragmentation (>30%), such as isolation with microfluidic chips, as well as special assisted reproduction methods, such as ICSI and PICSI.
Azoospermia / Retrograde ejaculation During retrograde ejaculation, the semen travels into the bladder and, as a result, the man...
Innovative lab techniques The causes of male infertility are addressed and the chances of success are maximized, based on...
Ultrasound It is often used to diagnose the causes of male infertility, but also problems linked to male sexuality....
Genetic Testing The advancements in molecular biology and genetics offer the possibility of examining the genes involved in sperm...
Hormone Testing A hormone test is a blood test that measures the levels of hormones, which play a major...
Investigation of male reproductive tract inflammation If the semen analysis indicates an infection (increased number of round cells, mucus,...
DNA Fragmentation Testing DNA fragmentation assay is the most important sperm function test. DNA fragmentation assay is the most...
Microbiological and Biochemical Analysis Microbiological analysis is recommended when there is a history of inflammation or indication such as...
Sperm activation / Sperm viability The total number of progressively motile sperm after sample treatment is calculated. The most...
Semen Analysis A semen analysis is the key test for investigating male infertility. It is performed in compliance with...